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This study uses UV ChIP-seq to identify novel CTCF-DNA interactions, revealing previously undetected binding sites and noncanonical motifs.

The paper links maternal obesity to hypoxia gene expression in term placenta and its association with offspring neurodevelopmental outcomes.

This paper presents a phased chromosome-level genome assembly for Syzygium luehmannii, annotated with NLR resistance genes to study susceptibility to myrtle rust.

The paper investigates retrotransposon mobilization in Drosophila spermatogenesis, finding that the nomad retrotransposon generates extrachromosomal DNA to prevent genomic instability.

This paper presents a chromosome-level genome assembly of Garra rufa, identifies heat shock-related genes, and highlights its evolutionary relationship to other cyprinid species.

This study constructs a mango pangenome to explore genetic diversity and evolution, identifying structural variations, SNPs, and trait-associated genes for breeding and conservation.

The paper presents chromosome-level genome assemblies for five Sinocyclocheilus species to aid in studying cave adaptation and conservation.

The paper uses single-molecule sequencing to show most DNA replication initiation in human cells occurs at dispersed sites, not just previously identified zones.

This study identifies two epigenetically-defined spatial niches in glioblastoma that influence cell state plasticity through local and long-range molecular signals.

GCfix corrects GC bias in cell-free DNA data across diverse coverages, outperforming existing methods with two new performance metrics.

The paper establishes Arachnopeziza species as a model system for studying powdery mildew fungi by generating their genome assemblies and demonstrating genetic modification capabilities.

The paper develops a high-throughput assay to test retrotransposon jumping activity and identifies variants that influence transposition.

The paper uses RNA sequencing in mice to identify transcriptome differences associated with ethanol preference, finding reduced gene-gene correlation in high-preferring mice.

The paper combines pangenomics and population genetics to identify chromosomal rearrangements, copy number variations, and transposon activity in wheat and rye powdery mildew isolates.

ONTraC uses a graph neural network to analyze spatial transcriptomics data, improving trajectory reconstruction and revealing microenvironment-dependent changes in gene regulation and cell interactions during development.

The paper presents a chromosome-level genome assembly of Bostrychia moritziana, revealing genome size expansion and genetic adaptations in red algae.

eLaRodON improves large genomic rearrangement detection in Oxford Nanopore data, outperforming existing tools with higher accuracy across multiple datasets.

The paper reports the genome of a heat-tolerant and euryhaline cyanobacterium, identifies its genomic features, and compares it to related strains to understand its adaptation mechanisms.

This study presents two high-quality rose genomes and constructs a Rosa pangenome to explore genetic diversity, evolution, and breeding potential in the genus Rosa.

This study shows that cancer-specific activation of retroelements disrupts gene function and tumour-promoting genes, with clinical and experimental evidence supporting these effects.