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This paper presents the chromosome-scale genome of Phyllanthus niruri, identifies candidate genes, and proposes a biosynthetic pathway for phyllanthin formation.

This paper describes an Illumina-based whole-genome sequencing method for measles virus, showing it can detect 10,000 genome copies with high accuracy.

The paper provides Andes virus sequencing datasets and evaluates a tiling amplicon scheme for benchmarking and optimizing bioinformatic pipelines.

This study analyzes 359 O118 STEC genomes to characterize their phylogenetic relationships, virulence factors, and resistance traits, identifying novel pathogenicity islands and genetic diversity.

The paper develops a method to detect and analyze NUMTs in human and non-human primate genomes, revealing their genomic features, population dynamics, and evolutionary implications.

The paper introduces a scale mixture model for metatranscriptomics data to improve differential expression analysis in inflammatory bowel disease, identifying new candidate genes not found by Gaussian methods.

SarcDBase is a tool that extracts and interprets genetic alterations from tumor sequencing data, showing high agreement with curated diagnoses in most cases.

This paper shows that AI, specifically AlphaFold2, redirected scientific attention toward novel research targets in structural biology, increasing engagement with understudied genes and proteins.

The paper generates a chromatin accessibility map of pea aphid brain and embryo using ATAC-seq, identifying tissue-specific regulatory elements and their relationship to gene expression.

This study examines how seed exposure to 5-azaC affects transcriptomic responses in Erodium cicutarium, revealing tissue- and age-specific gene regulation changes.

mafsmith reimplements vcf2maf in Rust, achieving faster and more efficient conversion of VCF files to MAF with identical output across multiple datasets.

The paper identifies novel RNA-guided nucleases with broad PAM diversity using structure-led metagenomic analysis, expanding genome editing capabilities.

Bio-BLIP is a multimodal architecture that integrates DNA, genes, proteins, and text to improve variant interpretation without task-specific fine-tuning, achieving better performance in variant prioritization and target gene prediction.

ICePop links genetic risk to disease-relevant cellular states by analyzing single-cell transcriptomics data across multiple traits, identifying 1,684 disease-cell type associations.

This study maps DNA replication origins in Trypanosoma brucei using stranded short nascent strand sequencing, revealing their sequence, structural, and chromatin features.

This study constructs a reliable PPI network for Magnaporthe oryzae using three computational methods, resulting in a database with 217,531 highly confident interactions.

The paper introduces DICE, a CRISPR screening method that improves scalability and robustness over SLICE in THP1 cells by using dual-guide RNA infection with Cas9 electroporation.

The paper identifies glial cell-specific regulatory elements and genetic risk modifiers in tau-related dementias using single-nucleus epigenomic profiling.

The paper presents the first chromosome-level genome assembly for the marbled teal, enabling analyses of inbreeding and genetic variation in this threatened species.

This paper uses NLP to analyze gut microbiome studies in malnourished African children, identifying microbial signatures and associations with malnutrition.