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The paper introduces an origami-based model to visualize amyloid beta-sheet structures and their topological arrangements, aiding in teaching amyloid folding and related concepts.

This study shows that PAI-1 deficiency leads to early cardiac hemorrhage and fibrosis under hemodynamic stress, with mutations in the protease-inhibitory domain causing similar pathology.

The paper identifies miR-219 and RalGPS as regulators of acute synaptic plasticity at Drosophila neuromuscular junctions through miRNA-mediated post-transcriptional control.

The paper identifies a genetic interaction between Adgrg6 and Sox9 that contributes to spinal stability and AIS-like pathology in mice.

This study quantifies cancer stemness in prostate cancer across progression stages, showing its association with therapy resistance, poor survival, and lineage plasticity.

The paper investigates functional properties of KCNH1 variants linked to neurodevelopmental disorders, finding most exhibit gain-of-function characteristics.

This study shows that engineered NK cells with a CD4-based CAR delay HIV rebound and alter the reservoir's composition in humanized mice.

This study uses PacBio HiFi sequencing to assemble complete Plasmodium falciparum genomes from natural infections, revealing full repertoires of immune-related genes.

This study identifies structural and energetic determinants of monobody 12D4 recognition of KRAS variants using simulations and redesign, revealing key interactions and mutations for improved selectivity.

This study uses yeast large-scale absolute quantitative proteomics to reveal universal principles of protein resource allocation among cellular organelles and its relationship to physiological parameters and species divergence.

KmerSignificance Score (KSS) prioritizes viral k-mers by integrating strain-distinguishing capacity, mutation impact, and functional importance, achieving superior classification performance and cross-dataset comparability.

This study compares proteomic profiles of strong and weak biofilm-forming Acinetobacter baumannii isolates to identify potential therapeutic targets.

The paper identifies three GCN2 activators, one of which works independently of GCN1, and describes its unique binding mechanism.

This study examines cryptic diversity in subarctic moss populations, revealing habitat-specific genetic differences and clonal structure that affect biodiversity estimates.

This study identifies the functional interplay between PBP1A and LdtJ in Acinetobacter baumannii, showing that disrupting their coordination weakens the cell envelope and increases colistin resistance.

This study uses acoustic telemetry to analyze movement patterns and habitat use of invasive blue crabs in a Mediterranean lagoon, revealing sex-specific behaviors and informing management strategies.

This study shows CD47 blockade enhances anti-GD2 phagocytosis in vitro but does not improve in vivo efficacy in neuroblastoma models.

The paper introduces FennoTraits, a dataset of plant functional traits and community composition from northern European flora, highlighting trait patterns and species distribution across seven study areas.

This study develops a fibroblast-derived matrix platform to investigate how tumor-associated EDA-FN-enriched matrices influence macrophage behavior in the tumor microenvironment.

Blender tissue cartography provides an intuitive tool for analyzing dynamic 3D microscopy data by converting complex 3D tissues into 2D projections for easier visualization and analysis.