Amyloid Folding: an Origami-Based Approach
The paper introduces an origami-based model to visualize amyloid beta-sheet structures and their topological arrangements, aiding in teaching amyloid folding and related concepts.
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Universidade Federal do Rio de JaneiroORCID 0000-0001-6020-0504Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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The paper introduces an origami-based model to visualize amyloid beta-sheet structures and their topological arrangements, aiding in teaching amyloid folding and related concepts.
Fernando de Sá Ribeiro, Luís Maurício T. R. Lima
This study investigates the relationship between temperature and B-factors in a trypsin-benzamidine complex, finding that B-factor variation is constant across temperature and not linked to conformational changes.
Fernando de Sá Ribeiro, Luís Maurício T. R. Lima
This study identifies a hydrophobic grease that enables X-ray diffraction data collection across a wide temperature range, from 100 K to 300 K, with minimal exposure time effects.
Daiane Oliveira Matias, Bruna Lima Roedel dos Santos, Aline França Martins…·Luís Maurício T. R. Lima
This study shows that dietary zinc restriction in adult mice causes irreversible allodynia and metabolic changes, which are reversed by zinc repletion.
Tháyna Sisnande, Felipe Lopes Brum, Daiane Oliveira Matias…·Luís Maurício T. R. Lima
The paper uses MALDI-imaging mass spectrometry to analyze pancreatic hormone proteoforms in mice, showing reduced peptide intermediates under zinc restriction.
Celimar Sinézia, Tháyna Sisnande, Luis Peña Icart, Luís Maurício T. R. Lima
This study develops and characterizes polymeric microparticles for oral delivery of pramlintide, showing prolonged release compared to intravenous administration.
Tháyna Sisnande, Cleverton K. Lima, Dayana Cabral da Silva…·Luís Maurício T. R. Lima
This study shows that zinc restriction in mice leads to increased β-cell hormone levels and pancreatic islet degeneration despite reduced islet size.