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CloneVI infers clonal structure from cell states in single-cell RNA-seq and ATAC-seq data, linking mitochondrial DNA mutations to specific cell states.

CryoID2 uses deep learning and sequence analysis to identify proteins and RNA from cryoEM maps, achieving high accuracy in molecular identification.

This paper develops a live bacterial system to reduce nicotine levels in blood and brain by enzymatic degradation in the gut, showing potential for non-systemic treatment of nicotine addiction.

This study identifies mechanotransduction pathways involved in chicken tendon development and shows how paralysis disrupts these processes.

This study examines how reduced watering affects hops growth and rhizospheric microbial communities across five cultivars, finding differential plant responses and consistent microbial associations with cultivar type.

The paper identifies distinct electrophysiological patterns in interdigitated default and frontoparietal networks using EEG-fMRI data.

The paper uses N-GLYcanyzer to monitor Trastuzumab biosimilar N-glycoform changes in a microperfusion process, identifying key parameters affecting glycoform evolution.

This study optimizes IVF procedures in common marmosets by identifying factors like progesterone levels and stimulation duration that improve embryo development and implantation rates.

The paper examines colony shape variation in Caribbean octocorals, finding that species identity, not colony size, primarily determines shape differences.

This study shows that repeated chlorpyrifos exposure in rats leads to long-term epigenetic and transcriptional changes in the hippocampus, including reduced BDNF and altered neuronal plasticity pathways, associated with a depressive-like phenotype.

This paper introduces vTRM, a framework to characterize WMH spatial patterns across age and sex, revealing distinct associations with aging, vascular, and neurodegenerative processes.

This study compares Eulerian and Lagrangian models of phytoplankton communities in an ocean circulation model, showing that particle-based methods produce distinct biogeography and diversity patterns.

This study shows that GFRAL neurons in the brainstem regulate intestinal structure and type 2 immunity through a vagal circuit, affecting food allergy, helminth infection, and colitis.

The paper shows cancer classifiers can achieve perfect accuracy by learning data source shortcuts rather than biological features, and introduces a method to detect and mitigate this issue.

This study identifies biosurfactant-producing microbial consortia from marine oil snow in western Hudson Bay and finds higher biosurfactant yields at lower temperatures.

This study evaluates the effects of organic fertilizer substitution on Dendrobium officinale yield and medicinal quality, finding that 40% substitution optimizes both growth and active compound content.

This paper develops bispecific VSV-G engagers to enable cell-type-specific delivery of viral vectors, demonstrating effectiveness in targeting tumor cells and generating CAR T cells.

This paper introduces a direct enzymatic bioconjugation platform using the flavin transferase ApbE, enabling site-specific conjugation of diverse payloads without intermediate chemical steps.