Author

A. Aizenshtadt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

S. Krauss· 5 shared S. R. Wilson· 4 shared E. Lundanes· 3 shared F. S. Skottvoll· 3 shared A. Golovin· 2 shared H. Roberg-Larsen· 2 shared H. Scholz· 2 shared I. L. Bogen· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersBiochemistry

S. Krauss

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Author profile →

5 papers

Recent·Most cited

Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids

C. Olsen, C. Wang, A. Aizenshtadt, S. Abadpour, E. Lundanes, F. S. Skottvoll, A. Golovin, M. Busek, S. Krauss, H. Scholz, S. R. Wilson

The paper develops an RPLC-MS/MS method to simultaneously measure insulin, somatostatin-14, and glucagon from stem cell-derived islet organoids on an organ-on-chip platform, showing functional hormone secretion.

ELECTROPHORESIS · Aug 13, 2023Peer-reviewedBiochemistry

Mass Spectrometry Reveals that Oxysterols are Secreted from Non-Alcoholic Fatty Liver Disease Induced Organoids

K. S. Komurcu, I. Wilhelmsen, J. L. Thorne, S. Krauss, S. R. Wilson, A. Aizenshtadt, H. Roberg-Larsen

The paper uses mass spectrometry to show that liver organoids secrete oxysterols, with 26-hydroxycholesterol being elevated in steatotic organoids and potentially acting as a biomarker for NAFLD.

bioRxiv · Feb 22, 2023Biochemistry

Pump-less, recirculating organ-on-a-chip (rOoC) platform

M. Busek, A. Aizenshtadt, T. Koch, A. Frank, L. Delon, M. Amirola-Martinez, A. Golovin, C. Dumas, J. Stokowiec, S. Gruenzner, E. Melum, S. Krauss

This paper introduces a pump-less organ-on-a-chip platform that enables directional flow through gravity and microfluidic design, demonstrating endothelialisation and hepatic organoid integration.

Lab on a Chip · Jan 1, 2023Peer-reviewedBioengineering

"Organoid-in-a-column" coupled on-line with liquid chromatography-mass spectrometry

S. Kogler, A. Aizenshtadt, S. Harrison, F. S. Skottvoll, H. E. Berg, S. Abadpour, H. Scholz, G. Sullivan, B. Thiede, E. Lundanes, I. L. Bogen, S. Krauss, H. Roberg-Larsen, S. R. Wilson

This paper demonstrates the integration of liver organoids with liquid chromatography-mass spectrometry for on-line drug metabolism analysis.

bioRxiv · Sep 8, 2020Bioengineering

Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies

F. S. Skottvoll, F. Hansen, S. Harrison, I. C. S. Boger, A. Mrsa, M. S. Restan, M. Stein, E. Lundanes, S. Pedersen-Bjergaard, A. Aizenshtadt, S. Krauss, G. J. Sullivan, I. L. Bogen, S. R. Wilson

This study demonstrates the use of electromembrane extraction (EME) combined with mass spectrometry to monitor drug metabolism in liver organoids.

bioRxiv · May 15, 2020Biochemistry