Author

A. Alatoom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. Sapudom· 2 shared J. Teo· 2 shared B. C. Quartey· 1 shared M. ElGindi· 1 shared P. Tipay· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersBioengineering

J. Sapudom

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2 papers

Recent·Most cited

Matrix fibril alignment and density modulate YAP-mediated T-cell immune suppression

J. Sapudom, A. Alatoom, P. Tipay, J. Teo

This study shows that dense and aligned collagen matrices suppress T-cell activation via YAP signaling, suggesting ways to improve immunotherapy by modulating T-cell responses in such environments.

bioRxiv · Mar 19, 2024 · PreprintBioengineering

Tissue-bound hyaluronan molecular weight as a regulator of dendritic cell immune potency

B. C. Quartey, J. Sapudom, M. ElGindi, A. Alatoom, J. Teo

This study investigates how different molecular weights of tissue-bound hyaluronan affect dendritic cell functions, finding that low MW HA enhances immature DC differentiation and antigen uptake, while medium and high MW HA increase cytokine secretion in matured DCs.

bioRxiv · Jun 6, 2023Bioengineering