What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds
J. Durairaj, A. M. Waterhouse, T. Mets, T. Brodiazhenko, M. Abdullah, G. Studer, M. Akdel, A. Andreeva, A. Bateman, T. Tenson, V. Hauryliuk, T. Schwede, J. Pereira
This work uses deep learning to uncover novel protein families and folds by analyzing sequence and structural data, adding new entries to Pfam and identifying a novel toxin-antitoxin system.
bioRxiv · Mar 14, 2023 · PreprintBioinformatics