A conserved mechanism regulates reversible amyloids via pH-sensing regions
G. Cereghetti, V. M. Kissling, L. M. Koch, A. Arm, P. Afanasyev, M. Linsenmeier, C. Eichmann, J. Zhou, Y. Cao, D. M. Pfizenmaier, S. Kroschwald, T. Wiegand, R. Cadalbert, D. Boehringer, R. Mezzenga, , M. Peter
This study identifies a conserved mechanism by which pH-sensing regions regulate reversible amyloid formation in pyruvate kinase across yeast and human cells.
bioRxiv · Mar 21, 2022 · PreprintCell Biology