Pharmacology & ToxicologybioRxiv
Innovative, rapid, high throughput method for drug repurposing in a pandemic - a case study of SARS-CoV-2 and COVID-19
S. O. Bello, A. Yunusa, A. A. Adamu…·I. Okoye
This study identifies potential drugs for COVID-19 by combining computational and wet-lab methods, finding that erythromycin, pyridoxine, folic acid, and retapamulin inhibit SARS-CoV-2 induced cytopathic effect in Vero cells at clinically achievable concentrations.
DOI 10.3389/fphar.2023.1130828