Data-driven discovery of innate immunomodulators via machine learning-guided high throughput screening
Y. Tang, J. Y. Kim, C. K. IP, A. Bahmani, Q. Chen, M. G. Rosenberger, A. P. Esser-Kahn, A. L. Ferguson
This study uses machine learning to guide high-throughput screening and discovers small molecules that modulate innate immune pathways, with some showing up to 15-fold suppression of NF-κB activity.
bioRxiv · Jun 26, 2023Immunology