Modelling Osteoarthritis pathogenesis through Mechanical Loading in an Osteochondral Unit-on-Chip
A. Mainardi, A. Boersch, P. Occhetta, R. Ivanek, M. Ehrbar, L. A. Krattiger, P. Oertle, M. Loparic, I. Martin, M. Rasponi, A. Barbero
This study develops an OCU-on-chip system to model OA pathogenesis under mechanical loading, identifying novel metabolic drivers and molecular targets for OA therapies.
bioRxiv · Aug 29, 2023Bioengineering