Optimal maturation of the SIV-specific CD8+ T-cell response after primary infection is associated with natural control of SIV. ANRS SIC study
C. Passaes, A. Millet, V. Madelain, V. Monceaux, A. David, P. Versmisse, N. Sylla, E. Gostick, D. A. Price, A. Blancher, N. Bosquet, G. Pancino, R. Le Grand, O. Lambotte, M. Muller-Trutwin, , A. Saez-Cirion
This study shows that optimal maturation of SIV-specific CD8+ T-cells correlates with natural control of SIV infection in macaques, with controllers developing more potent antiviral responses over time.
bioRxiv · Dec 20, 2019Immunology