Author

A. Botto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gregori· 1 shared A. J. M. Zweemer· 1 shared B. van de Water· 1 shared C. Bergonzini· 1 shared E. Giovannetti· 1 shared E. H. J. Danen· 1 shared F. Finamore· 1 shared G. Mantini· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Gregori

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Author profile →

1 paper

Recent·Most cited

ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells

C. Bergonzini, A. Gregori, T. M. S. Hagens, V. E. van der Noord, B. van de Water, A. J. M. Zweemer, M. Capula, G. Mantini, A. Botto, F. Finamore, I. Garajova, L. A. McDonnell, T. Schmidt, E. Giovannetti, E. H. J. Danen

This study identifies ABCB1 overexpression via locus amplification as a conserved mechanism of paclitaxel resistance in PDAC and shows that targeting ABCB1 can sensitize resistant cells to treatment.

bioRxiv · May 30, 2023 · PreprintCancer Biology