Author

A. Bruch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. G. Blango· 3 shared O. Kniemeyer· 3 shared A. A. Brakhage· 2 shared A. A. Kelani· 2 shared C. Visser· 2 shared F. Rivieccio· 2 shared G. Panagiotou· 2 shared S. Schaeuble· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

M. G. Blango

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3 papers

Recent·Most cited

tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.

A. Bruch, V. Lazarova, M. Berg, T. Krueger, S. Schaeuble, A. A. Kelani, B. Mertens, P. Lehenberger, O. Kniemeyer, S. Kaiser, G. Panagiotou, F. Gsaller, M. G. Blango

This study shows that tRNA hypomodification in Aspergillus fumigatus leads to 5-fluorocytosine resistance through premature activation of a cross-pathway control system.

bioRxiv · Feb 19, 2024 · PreprintMicrobiology

Disruption of the Aspergillus fumigatus RNA interference machinery alters the conidial transcriptome.

A. A. Kelani, A. Bruch, F. Rivieccio, C. Visser, T. Krueger, D. Weaver, X. Pan, S. Schaeuble, G. Panagiotou, O. Kniemeyer, M. J. Bromley, P. Bowyer, A. E. Barber, A. A. Brakhage, M. G. Blango

This study investigates the role of RNA interference in Aspergillus fumigatus by analyzing genetic variation and functional outcomes of RNAi component knockouts.

bioRxiv · Jul 28, 2022Microbiology

PLB-985 neutrophil-like cells as a model to study Aspergillus fumigatus pathogenesis

M. Rafiq, F. Rivieccio, A.-K. Zimmermann, C. Visser, A. Bruch, T. Krüger, K. Gonzalez Rojas, O. Kniemeyer, M. G. Blango, A. A. Brakhage

This paper demonstrates that differentiated PLB-985 cells can model key aspects of A. fumigatus interactions with human neutrophils, including phagocytosis, extracellular trap release, and antifungal vesicle production.

bioRxiv · Jul 28, 2021Microbiology