M. Berg

tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.

This study shows that tRNA hypomodification in Aspergillus fumigatus leads to 5-fluorocytosine resistance through premature activation of a cross-pathway control system.

Reconstructing microvascular network skeletons from 3D images: what is the ground truth?

This paper evaluates skeletonisation algorithms for 3D vascular networks, introducing a super-metric to assess and optimize their performance across different datasets.

An Enterobacteriaceae bloom in aging animals is restrained by the gut microbiome

The paper identifies an Enterobacteriaceae bloom in aging animals as a common feature, showing its link to immune decline and susceptibility to infection, while highlighting the role of commensal competition in healthy aging.

A multivariate network analysis of ring- and diffuse-porous tree xylem vasculature segmented by convolutional neural networks

This paper analyzes xylem vessel networks in six tree species using convolutional neural networks and network metrics to relate structural properties to hydraulic vulnerability and drought resistance.

An integrated cell atlas of the human lung in health and disease

The paper integrates 46 single-cell datasets to create the Human Lung Cell Atlas, improving cell annotation and uncovering gene modules linked to demographics and anatomy.

Host population diversity as a driver of viral infection cycle in wild populations of green sulfur bacteria with long standing virus-host interactions

This study examines viral infection dynamics in green sulfur bacteria, finding that multiple viruses, including lysogenic ones, co-infect host populations and that host diversity may influence the lytic/lysogenic switch.

A cellular census of healthy lung and asthmatic airway wall identifies novel cell states in health and disease

The paper uses single-cell transcriptomics to identify novel cell states in healthy and asthmatic lung tissues, revealing changes in cell communication and immune responses.