Lamin-related congenital muscular dystrophy alters mechanical signaling and skeletal muscle growth
D. J. Owens, J. Messeant, S. Moog, M. Viggars, A. Ferry, K. Mamchaoui, E. Lacene, N. Romero, A. Brull, G. Bonne, G. S. Butler-Bowne, C. Coirault
This study investigates how LMNA mutations affect skeletal muscle growth and mechanical signaling in muscle stem cells and mouse models, finding impaired differentiation and hypertrophy in LMNA-CMD.
bioRxiv · Aug 6, 2020Physiology