A. Ferry

Functional Diversity of Memory CD8 T Cells is Spatiotemporally Imprinted

The paper investigates how spatial location influences the functional diversity of memory CD8 T cells by analyzing their transcriptomes in the small intestine.

Different outcomes of endurance and resistance exercise in skeletal muscles of Oculopharyngeal muscular dystrophy.

This study compares the effects of endurance and resistance exercise on OPMD skeletal muscle in mice, finding that resistance exercise reduces PABPN1 aggregates and reverses muscle atrophy, while endurance exercise increases aggregates and collagen deposition.

AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion

This study shows that AMPKα2 regulates myonuclear accretion in muscle stem cells, essential for muscle regeneration.

The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle

This study shows that Prox1 gene transfer reduces muscle fragility in exercised dystrophic mdx mice but not sedentary ones, suggesting a synergistic effect with chronic exercise.

Lamin-related congenital muscular dystrophy alters mechanical signaling and skeletal muscle growth

This study investigates how LMNA mutations affect skeletal muscle growth and mechanical signaling in muscle stem cells and mouse models, finding impaired differentiation and hypertrophy in LMNA-CMD.

Desmin is a modifier of dystrophic muscle features in Mdx mice

This study shows that desmin deletion in Mdx mice worsens muscle weakness, fragility, and fatigue resistance, while desmin gene transfer improves these features.

Differential physiological role of BIN1 isoforms in skeletal muscle development, function and regeneration

This study investigates the differential roles of BIN1 isoforms in skeletal muscle development, function, and regeneration using knockout mice, finding that ubiquitous BIN1 is essential for development while muscle-specific isoforms are critical for regeneration.