Staphyloccocus aureus biofilm, in the absence of planktonic bacteria, produces factors that activate counterbalancing inflammatory and immune-suppressive genes in human monocytes
R. D. Bell, E. A. Cann, B. Mishra, M. Valencia, Q. Zhang, X. Yang, A. Carli, M. Bostrom, L. Ivashkiv
This study shows S. aureus biofilm produces soluble factors that activate inflammatory and immune-suppressive genes in human monocytes, suggesting a role for these factors in modulating immune responses in PJI.
bioRxiv · Oct 6, 2023 · PreprintImmunology