M. Bostrom

Staphyloccocus aureus biofilm, in the absence of planktonic bacteria, produces factors that activate counterbalancing inflammatory and immune-suppressive genes in human monocytes

This study shows S. aureus biofilm produces soluble factors that activate inflammatory and immune-suppressive genes in human monocytes, suggesting a role for these factors in modulating immune responses in PJI.

Elevated pyrimidine dimer formation at distinct genomic bases underlie promoter mutation hotspots in UV-exposed cancers

The paper shows that UV-induced mutations in cancer promoters are due to base-specific increases in pyrimidine dimer formation, not inhibited repair.