Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome
J. P. Tosar, M. Segovia, F. Gambaro, Y. Akiyama, P. Fagundez, B. Costa, T. Possi, M. Hill, P. Ivanov, A. Cayota
The paper develops RI-SEC-seq to analyze nonvesicular exRNAs, revealing extracellular ribosomes and tRNAs that resist degradation and act as damage-associated molecular patterns.
bioRxiv · Jan 29, 2020Cell Biology