A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies
B. Costa, M. N. Fletcher, P. Boskovic, E. L. Ivanova, T. Eisemann, S. Lohr, L. Bunse, M. Loewer, S. Burchard, A. Korshunov, H.-K. Liu, M. Platten, B. Radlwimmer, P. Angel, H. Peterziel
This study develops a glioblastoma cell line from a genetic mouse model that mimics human glioblastoma features, enabling preclinical testing of immunotherapies.
bioRxiv · Mar 16, 2020 · PreprintCancer Biology