Reprogramming Adeno-Associated Virus Tropism Via Displayed Peptides Tiling Receptor-Ligands
A. Portell, K. M. Ford, A. Suhardjo, J. Rainaldi, M. N. Bublik, M. Sanghvi, A. Kumar, M. K. Wing, N. D. Palmer, D. A. Le, N. Kalahasti, A. Dailamy, P. Mali
This paper reprograms AAV tropism by displaying tiling peptides of receptor-ligands, identifying variants with improved tissue transduction and validated interactions.
bioRxiv · Sep 26, 2022 · PreprintBioengineering