The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins
A. Daulat, M. S. Wagner, S. Audebert, M. Kowalczewska, J. Ariey-Bonnet, P. Finetti, F. Bertucci, L. Camoin, J.-P. Borg
This study identifies MINK1 as a kinase that phosphorylates LL5β, a component of the PRICKLE1 complex, promoting cell migration in triple-negative breast cancer and associating with poor metastasis-free survival.
bioRxiv · Sep 2, 2021Cell Biology