The early macrophage response to pathogens requires dynamic regulation of the nuclear paraspeckle
S. Azam, K. S. Armijo, C. G. Weindel, A. Devigne, S. Nakagawa, T. Hirose, S. L. Carpenter, R. O. Watson, K. L. Patrick
This paper shows that the nuclear paraspeckle dynamically regulates inflammatory gene expression in macrophages, essential for controlling pathogen replication.
bioRxiv · May 11, 2023Immunology