A Mycobacterium tuberculosis effector targets mitochondrion, controls energy metabolism and limits cytochrome c exit.
M. Martin, A. deVisch, P. Barthe, O. Turapov, T. Aydogan, L. Heriaud, J. Gracy, G. Mukamolova, F. Letourneur, M. Cohen-Gonsaud
This study identifies Rv1813c, a Mycobacterium tuberculosis effector that targets mitochondria, enhances ATP production, and delays cytochrome c release, thereby modulating host metabolism and apoptosis.
bioRxiv · Jan 31, 2021Microbiology