A Mycobacterium tuberculosis effector targets mitochondrion, controls energy metabolism and limits cytochrome c exit.
M. Martin, A. deVisch, P. Barthe…·M. Cohen-Gonsaud
This study identifies Rv1813c, a Mycobacterium tuberculosis effector that targets mitochondria, enhances ATP production, and delays cytochrome c release, thereby modulating host metabolism and apoptosis.