Clostridioides difficile binary toxin binding component (CDTb) increases virulence in a hamster model
M. Simpson, T. Bilverstone, J. L. Leslie, A. Donlan, M. J. Uddin, W. Petri, N. Marin, C. Schwan, S. Kuehne, N. P. Minton, W. A. Petri
This study shows that CDTb, a component of C. difficile binary toxin, contributes to virulence by inducing inflammation and restoring virulence in a hamster model when expressed alone.
bioRxiv · Aug 3, 2021Microbiology