Author

C. Schwan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

M. Simpson· 2 shared W. Petri· 2 shared A. Donlan· 1 shared A. Frisbee· 1 shared D. Virant· 1 shared J. Knerr· 1 shared J. L. Leslie· 1 shared J. Winkelmeier· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

M. Simpson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clostridioides difficile binary toxin binding component (CDTb) increases virulence in a hamster model

M. Simpson, T. Bilverstone, J. L. Leslie, A. Donlan, M. J. Uddin, W. Petri, N. Marin, C. Schwan, S. Kuehne, N. P. Minton, W. A. Petri

This study shows that CDTb, a component of C. difficile binary toxin, contributes to virulence by inducing inflammation and restoring virulence in a hamster model when expressed alone.

bioRxiv · Aug 3, 2021Microbiology

Clostridium difficile binary toxin (CDT) is recognized by the TLR2/6 heterodimer to induce an NF-κB response

M. Simpson, A. Frisbee, P. Kumar, C. Schwan, K. Aktories, W. Petri

The paper shows that CDT is recognized by the TLR2/6 heterodimer, leading to NF-κB and MAPK pathway activation in mice during CDI.

bioRxiv · Sep 8, 2020 · PreprintImmunology

Post-mitotic expansion of cell nuclei requires ACTN4-mediated nuclear actin filament bundling

R. Grosse, S. Krippner, J. Winkelmeier, C. Schwan, J. Knerr, D. Virant, U. Endesfelder

This study identifies ACTN4 as essential for postmitotic nuclear expansion by promoting actin filament bundling in the nucleus.

bioRxiv · Apr 29, 2020Cell Biology