Cancer BiologybioRxivPreprint
Acetyl transferase EP300 deficiency leads to chronic replication stress mediated by defective fork protection at stalled replication forks
A. Barreto-Galvez, M. Niljikar, J. Gagliardi…·A. Madireddy
This paper shows that EP300 deficiency causes chronic replication stress and genomic instability in ATLL cells by impairing fork protection and leading to DNA damage and mitotic defects.
DOI 10.1101/2023.04.29.538781