Author

A. Shaikh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Barreto-Galvez· 1 shared A. Durbin· 1 shared A. Juwarwala· 1 shared A. Lohith· 1 shared A. Madireddy· 1 shared A. Pradeep· 1 shared B. H. Ye· 1 shared E. A. McMillan· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Barreto-Galvez

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Acetyl transferase EP300 deficiency leads to chronic replication stress mediated by defective fork protection at stalled replication forks

A. Barreto-Galvez, M. Niljikar, J. Gagliardi, R. Zhang, A. Juwarwala, A. Pradeep, V. Kumar, P. Tiwari, A. Shaikh, K. Sharma, J. Gerhardt, J. Cao, K. Kataoka, A. Durbin, J. Qi, , A. Madireddy

This paper shows that EP300 deficiency causes chronic replication stress and genomic instability in ATLL cells by impairing fork protection and leading to DNA damage and mitotic defects.

bioRxiv · Apr 29, 2023 · PreprintCancer Biology

High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling

J. B. MacMillan, R. G. Linington, S. K. Hight, R. S. Lokey, W. Bray, K. Kurita, A. Shaikh, J. Haeckl, S. La, A. Lohith, E. A. McMillan, M. A. White, T. N. Clark, J. Lee, F. Carnevale, , S. Wei

This paper introduces a platform integrating phenotypic screening and metabolomics to improve mechanism of action prediction for natural products, leading to the discovery of novel bioactive compounds.

bioRxiv · Jun 8, 2022Pharmacology & Toxicology