Author

A. E. Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Approach:biophysical modeling· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

C. Neale· 1 shared S. Sarkar· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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2 top collaborators · 0 mutual co-author links

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1 shared paperBiophysics

C. Neale

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2 papers

Recent·Most cited

The plasma membrane as a competitive inhibitor and positive allosteric modulator of KRas4B signaling

C. Neale, A. E. Garcia

The paper uses molecular dynamics simulations to show that anionic lipids influence Ras orientation, which affects its signaling competence and suggests a new drug target for Ras-driven cancers.

Biophysical Journal · Mar 1, 2020Peer-reviewedBiophysics

Presence or absence of Ras-dimerization shows distinct kinetic signature in Ras-Raf interaction

S. Sarkar, A. E. Garcia

The paper uses multi-scale simulations to distinguish Ras dimerization-dependent from -independent Ras-Raf activation mechanisms.

bioRxiv · Oct 18, 2019Biophysics