Non-invasive monitoring of drug action: a new live in vitro assay design for Chagas' disease drug discovery
A. F. Fesser, O. Braissant, F. Olmo, J. M. Kelly, M. Kaiser, P. Maeser
This paper introduces a live in vitro assay using eGFP-expressing Trypanosoma cruzi to monitor drug action over 6 days, revealing pharmacodynamic profiles of benznidazole and posaconazole.
bioRxiv · Jan 15, 2020Microbiology