Author

P. Maeser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Organism:non-human primate· 1 Organism:plant (other)· 1

Frequent Co-Authors

N. Wiedemar· 2 shared A. F. Fesser· 1 shared A. Hempelmann· 1 shared A. Passecker· 1 shared A.-M. Zeeman· 1 shared C. E. Stebbins· 1 shared C. H. M. Kocken· 1 shared E. Hitz· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

N. Wiedemar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Persistence of Plasmodium cynomolgi hypnozoites in cynomolgus monkey iPS-derived hepatocytes

M. Pellisson, A.-M. Zeeman, T. Doll, L. Kirchhofer-Allan, S. Schuierer, G. Roma, E. L. Flannery, S. A. Mikolajczak, C. H. M. Kocken, P. Maeser, M. Rottmann, M. Mueller

This study develops an in vitro model using cynomolgus monkey iPS-derived hepatocytes to study Plasmodium cynomolgi hypnozoite formation and liver stage dormancy, aiding drug discovery.

bioRxiv · Nov 16, 2021 · PreprintCell Biology

The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

E. Hitz, N. Wiedemar, A. Passecker, N. M. B. Brancucci, I. Vakonakis, P. Maeser, T. S. Voss

This study identifies PfPDK1 as an essential upstream activator of PfPKAc in malaria parasites, crucial for parasite survival and a potential drug target.

bioRxiv · May 27, 2021Microbiology

A Parasite Coat Protein Binds Suramin to Confer Drug Resistance

J. Zeelen, M. van Straaten, J. Verdi, A. Hempelmann, H. Hashemi, K. Perez, P. D. Jeffrey, S. Haelg, N. Wiedemar, P. Maeser, F. N. Papavasiliou, C. E. Stebbins

This study identifies that the trypanosome VSGsur protein binds suramin, conferring drug resistance, and shows this interaction is critical for resistance.

bioRxiv · Jun 4, 2020 · PreprintMicrobiology

Non-invasive monitoring of drug action: a new live in vitro assay design for Chagas' disease drug discovery

A. F. Fesser, O. Braissant, F. Olmo, J. M. Kelly, M. Kaiser, P. Maeser

This paper introduces a live in vitro assay using eGFP-expressing Trypanosoma cruzi to monitor drug action over 6 days, revealing pharmacodynamic profiles of benznidazole and posaconazole.

bioRxiv · Jan 15, 2020Microbiology