Small Interactor of PKD2 (SIP), a novel PKD2-related single-pass transmembrane protein, is required for proteolytic processing and ciliary import of Chlamydomonas PKD2
P. Das, B. Mekonnen, A. V. Ingle, E. B. Workman, A. Feather, P. Liu, K. Lechtreck
This study identifies SIP as a novel PKD2-interacting protein essential for PKD2 proteolytic processing and ciliary import in Chlamydomonas, affecting ciliary function and motility.
bioRxiv · Jun 13, 2023Cell Biology