Structural insights into regulation of the PEAK3 scaffold by 14-3-3
H. Torosyan, M. D. Paul, A. Forget, M. Lo, D. Diwanji, K. Pawlowski, N. J. Krogan, N. Jura, K. A. Verba
This paper reports the cryo-EM structure of PEAK3 pseudokinase in complex with 14-3-3, revealing an asymmetric binding mechanism and identifying Protein Kinase D as a regulator.
bioRxiv · Sep 1, 2022 · PreprintBiophysics