Author

M. Lo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. D. Paul· 3 shared D. Diwanji· 2 shared H. Torosyan· 2 shared N. Jura· 2 shared A. Belkina· 1 shared A. Diallo· 1 shared A. E. Tseng· 1 shared A. F. Brilot· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBiophysics

M. D. Paul

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Aberrant macrophage activation and maladaptive lung repair promote tuberculosis progression uniquely in the lung

S. M. Yabaji, S. Lata, A. E. Tseng, P. B. Araveti, M. Lo, I. Gavrish, A. K. O'Connel, H. P. Gertje, A. Belkina, C. E. Thurman, H. Kiyokawa, D. N. Kotton, S. Tan, J. J. Endsley, W. R. Bishai, , I. Kramnik

This study identifies aberrant macrophage activation and maladaptive lung repair as key factors promoting tuberculosis progression in the lung using a novel mouse model.

bioRxiv · Oct 17, 2023 · PreprintImmunology

Structural insights into regulation of the PEAK3 scaffold by 14-3-3

H. Torosyan, M. D. Paul, A. Forget, M. Lo, D. Diwanji, K. Pawlowski, N. J. Krogan, N. Jura, K. A. Verba

This paper reports the cryo-EM structure of PEAK3 pseudokinase in complex with 14-3-3, revealing an asymmetric binding mechanism and identifying Protein Kinase D as a regulator.

bioRxiv · Sep 1, 2022 · PreprintBiophysics

Actin dynamics regulation by TTC7A/PI4KIIIα axis limits DNA damage and cell death during leukocyte migration

T. Gajardo, M. Lo, M. Bernard, C. Leveau, M.-T. El-Daher, M. Kurowska, G. Le Lay, D. Moshous, B. Neven, A. Fischer, G. Menasche, G. de Saint Basile, P. Vargas, F. E. Sepulveda

This study shows TTC7A deficiency impairs leukocyte migration, leading to DNA damage and cell death during chemotaxis in dense environments.

bioRxiv · Oct 14, 2021 · PreprintImmunology

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

M. Gupta, C. M. Azumaya, M. Moritz, S. Pourmal, A. Diallo, G. E. Merz, G. M. Jang, M. Bouhaddou, A. Fossati, A. F. Brilot, D. Diwanji, E. Hernandez, N. Herrera, H. T. Kratochvil, V. L. Lam, , K. I Pawar

The paper uses cryo-EM and AlphaFold2 to determine the structure of SARS-CoV-2 Nsp2, revealing its zinc-binding site and potential interactions with host proteins.

bioRxiv · May 10, 2021 · PreprintBiophysics

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

M. Lo, A. Sharir, M. D. Paul, H. Torosyan, C. Agnew, D. R. Raleigh, N. Jura, O. D. Klein

This study identifies CNPY4 as a negative regulator of the Hedgehog pathway by modulating membrane sterol lipid levels, revealing a new mechanism of pathway regulation.

bioRxiv · Mar 15, 2021Biochemistry