Synthetic Natural Product-Inspired Peptides
M. Hostetler, C. Smith, S. Nelson, Z. Budimir, R. Modi, I. Woolsey, A. Frerk, B. Baker, J. Gantt, E. I. Parkinson
This study introduces SNaPP, a method combining bioinformatics and chemical synthesis to discover novel bioactive peptides inspired by natural products, identifying 14 antibacterial peptides including activity against multidrug-resistant bacteria.
bioRxiv · Jun 15, 2021 · PreprintMicrobiology