Author

B. Baker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 3 Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:metagenomics· 2

Frequent Co-Authors

L. Rieth· 2 shared R. Modi· 2 shared R. Sharma· 2 shared A. Ali· 1 shared A. Andren· 1 shared A. Chowdhury· 1 shared A. E. Stis· 1 shared A. Frerk· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersBioengineering

L. Rieth

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Extremely acidic proteomes and metabolic flexibility in bacteria and highly diversified archaea thriving in geothermal chaotropic brines

A. Gutierrez-Preciado, B. Dede, B. Baker, L. Eme, D. Moreira, P. Lopez-Garcia

The paper analyzes metagenomes and proteomes from geothermal brines to show that archaea and bacteria have highly acidic proteomes and metabolic flexibility in extreme salinity conditions.

bioRxiv · Mar 10, 2024Microbiology

A 20-year time-series of a freshwater lake reveals seasonal dynamics and environmental drivers of viral diversity, ecology, and evolution

Z. Zhou, P. Q. Tran, C. Martin, R. R. Rohwer, B. Baker, K. McMahon, K. Anantharaman

The paper analyzes a 20-year viral time-series in a freshwater lake to uncover seasonal dynamics, environmental drivers, and evolutionary patterns of viral diversity and ecology.

bioRxiv · Feb 6, 2024Microbiology

Matrix architecture and mechanics regulate myofibril organization, costamere assembly, and contractility of engineered myocardial microtissues

S. J. DePalma, J. Jillberto, A. E. Stis, D. D. Huang, J. Lo, C. D. Davidson, A. Chowdhury, M. E. Jewett, H. Kobeissi, C. S. Chen, E. Lejeune, A. S. Helms, D. A. Nordsletten, B. Baker

This study investigates how matrix stiffness and alignment affect the structure and contractility of engineered myocardial tissues made from iPSC-derived cardiomyocytes.

bioRxiv · Oct 20, 2023Bioengineering

Sulfide oxidation promotes hypoxic angiogenesis and neovascularization

R. Kumar, V. Vitvitsky, P. Seth, H. L. Hiraki, H. Bell, A. Andren, R. Singhal, B. Baker, C. A. Lyssiotis, Y. M. Shah, R. Banerjee

This study shows that sulfide oxidation via SQOR promotes hypoxic angiogenesis and neovascularization by reprogramming metabolic pathways in endothelial cells.

bioRxiv · Mar 14, 2023Biochemistry

Simultaneous Spectral Differentiation of Multiple Fluorophores in Super-resolution Imaging Using a Glass Phase Plate

S. I. Fernando, J. T. Martineau, R. J. Hobson, T. N. Vu, B. Baker, B. Mueller, R. Menon, E. M. Jorgensen, J. Gerton

This paper introduces a method to simultaneously image and distinguish multiple fluorophores in super-resolution microscopy using a phase plate and computational algorithm.

bioRxiv · Jul 11, 2022 · PreprintBiophysics

Synthetic Natural Product-Inspired Peptides

M. Hostetler, C. Smith, S. Nelson, Z. Budimir, R. Modi, I. Woolsey, A. Frerk, B. Baker, J. Gantt, E. I. Parkinson

This study introduces SNaPP, a method combining bioinformatics and chemical synthesis to discover novel bioactive peptides inspired by natural products, identifying 14 antibacterial peptides including activity against multidrug-resistant bacteria.

bioRxiv · Jun 15, 2021 · PreprintMicrobiology

High-Stability Polyimide-based Flexible Electrodes with IrOx to Interface the Mouse Vagus Nerve

T. Sun, J. D. Falcone, C. Crosfield, M. F. Lopez, J. Peragine, R. Modi, R. Sharma, B. Baker, G. Anderson, S. Savani, C. Li, E. H. Chang, H. Sohal, L. Rieth

This paper develops flexible polyimide-based electrodes with IrOx for interfacing mouse vagus nerve, showing stable performance and efficacy in stimulating physiological responses.

bioRxiv · May 10, 2021 · PreprintBioengineering

2′-5′-Oligoadenylate synthetase-like protein inhibits intracellular M. tuberculosis replication and promotes proinflammatory cytokine secretion

G. Leisching, A. Ali, V. Cole, B. Baker

This study shows that OASL inhibits M. tuberculosis replication and promotes proinflammatory cytokine secretion in THP-1 cells.

bioRxiv · Oct 28, 2019Cell Biology

Analytical characterization of Parylene-C degradation mechanisms on Utah arrays: evaluation of in vitro Reactive Accelerated Aging model compared to multiyear in vivo implantation

R. Caldwell, M. G. Street, R. Sharma, P. Takmakov, B. Baker, L. Rieth

This study compares in vitro Reactive Accelerated Aging of Parylene-C coated Utah arrays to in vivo degradation over 3.25 years in feline nerve, finding similar physical damage but distinct chemical changes.

bioRxiv · Aug 24, 2019Bioengineering