Author

A. Geisel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. Hopf· 2 shared A. Marx· 1 shared B. C. Froehlich· 1 shared C. Graf· 1 shared C. Marsching· 1 shared C. Ramallo Guevara· 1 shared D. Abu Sammour· 1 shared J.-H. Rabe· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

C. Hopf

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2 papers

Recent·Most cited

Label-free Assessment of Complement-Dependent Cytotoxicity of Therapeutic Antibodies via a Whole-Cell MALDI Mass Spectrometry Bioassay

S. Schmidt, A. Geisel, T. Enzlein, B. C. Froehlich, L. Pritchett, M. Verneret, C. Graf, C. Hopf

This study develops a label-free MALDI-TOF mass spectrometry bioassay to assess complement-dependent cytotoxicity of Rituximab, identifying metabolite markers and demonstrating robust concentration-response characteristics.

bioRxiv · May 3, 2024Biochemistry

Quantitative Mass Spectrometry Imaging Reveals Mutation Status-independent Lack of Imatinib Penetration into Liver Metastases of Gastrointestinal Stromal Tumors

D. Abu Sammour, C. Marsching, A. Geisel, K. Erich, S. Schulz, C. Ramallo Guevara, J.-H. Rabe, A. Marx, P. Findeisen, P. Hohenberger, C. Hopf

The paper uses MSI to show imatinib does not penetrate GIST liver metastases, despite being present in healthy liver tissue, suggesting mutation-independent resistance.

bioRxiv · Feb 27, 2019Pharmacology & Toxicology