Author

A. Gentles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. E. Brook· 2 shared H. C. Ranaivoson· 2 shared J.-M. Heraud· 2 shared N. A. F. Ravelomanantsoa· 2 shared S. Andry· 2 shared A. Andrianiaina· 1 shared A. Delgado-Gonzalez· 1 shared A. L. Kistler· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersEcology

C. E. Brook

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Reproduction, seasonal morphology, and juvenile growth in three Malagasy fruit bats

A. Andrianiaina, S. Andry, A. Gentles, S. Guth, J.-M. Heraud, H. C. Ranaivoson, N. A. F. Ravelomanantsoa, T. Treuer, C. E. Brook

This paper documents seasonal reproductive patterns, morphological traits, and juvenile growth in three Malagasy fruit bat species to inform conservation and public health efforts.

bioRxiv · Oct 28, 2021Ecology

Full genome Nobecovirus sequences from Malagasy fruit bats define a unique evolutionary history for this coronavirus clade

G. Kettenburg, A. L. Kistler, H. C. Ranaivoson, S. Andry, J. L. DeRisi, A. Gentles, V. Raharinosy, T. H. Randriambolamanantsoa, N. A. F. Ravelomanantsoa, C. M. Tato, P. Dussart, J.-M. Heraud, C. E. Brook

The paper reports full genome sequences of Nobecoviruses from Malagasy fruit bats, revealing distinct phylogenetic clades and recombination events.

bioRxiv · Sep 29, 2021Evolutionary Biology

High-Grade Serous Ovarian Tumor Cells Modulate NK Cell Function to Create an Immune-Tolerant Microenvironment

V. D. Gonzalez, Y.-W. Huang, S.-Y. Chen, A. Delgado-Gonzalez, K. Donoso, A. Gentles, K. Sachs, E. Porpiglia, W. Fantl

This study identifies CD9 as a novel therapeutic target in high-grade serous ovarian cancer by showing tumor cells modulate NK cell function through trogocytosis.

bioRxiv · Nov 20, 2020Immunology

NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma

K. Brennan, J. H. Shin, J. K. Tay, M. Prunello, A. Gentles, J. B. Sunwoo, O. Gevaert

This study identifies an NSD1-inactivated, DNA hypomethylated, immune cold subtype in lung and head and neck squamous cell carcinomas, linked to poor immune infiltration and potential immunotherapy resistance.

bioRxiv · Oct 20, 2017Cancer Biology