MicrobiologybioRxiv
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution
T. N. Starr, A. J. Greaney, W. W. Hannon…·J. D. Bloom
The paper analyzes epistatic shifts in SARS-CoV-2 RBD mutations across variants to understand how they influence ACE2 binding and future evolution.
DOI 10.1126/science.abo7896