BioengineeringbioRxiv
Amino acid substitutions in human growth hormone affect coiled-coil content and receptor binding
DOI 10.1371/journal.pone.0282741
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2 papers
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N. Österlund, M. Lundqvist, L. I. Ilag…·C. Emanuelsson
This study shows DNAJB6 captures Aβ oligomers via S/T residues, inhibiting amyloid nucleation by binding pre-nucleation aggregates directly detected by native mass spectrometry.