Reconstitution of mammalian Cleavage Factor II involved in 3’ processing of mRNA precursors
P. Schaefer, C. Tueting, L. Schoenemann, U. Kuehn, T. Treiber, N. Treiber, C. Ihling, A. Graber, W. Keller, G. Meister, A. Sinz, E. Wahle
This study reconstitutes mammalian Cleavage Factor II as a heterodimer of hPcf11 and hClp1, showing its activity in RNA cleavage and RNA binding preferences.
bioRxiv · Aug 16, 2018Biochemistry