BiochemistrybioRxiv
Reconstitution of mammalian Cleavage Factor II involved in 3’ processing of mRNA precursors
P. Schaefer, C. Tueting, L. Schoenemann…·E. Wahle
This study reconstitutes mammalian Cleavage Factor II as a heterodimer of hPcf11 and hClp1, showing its activity in RNA cleavage and RNA binding preferences.