Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors
Q. Hu, J. Espejo Valle-Inclan, R. Dahiya, A. Guyer, A. Mazzagatti, E. G. Maurais, J. L. Engel, I. Cortes-Ciriano, P. Ly
This study shows that non-homologous end joining (NHEJ) is the main pathway causing complex genomic rearrangements during chromothripsis from mitotic errors.
bioRxiv · Aug 10, 2023 · PreprintCell Biology