Unpredictability of the fitness effects of antimicrobial resistance mutations across environments in Escherichia coli
A. Hinz, A. Amado, R. Kassen, C. Bank, A. Wong
This study shows that the fitness effects of antimicrobial resistance mutations vary widely across genetic backgrounds and environments in Escherichia coli, challenging assumptions about their predictability.
bioRxiv · Oct 25, 2023 · PreprintEvolutionary Biology