HIV-1 promoter is gradually silenced when integrated into BACH2
A. Inderbitzin, Y. L. Kok, L. Jörimann, A. Kelley, K. Neumann, D. Heinzer, T. Cathomen, K. J. Metzner
This study shows that HIV-1 promoters integrated into BACH2 are gradually silenced over time in Jurkat T-cells, without affecting BACH2 expression, potentially contributing to HIV-1 persistence.
PeerJ · Nov 24, 2020Peer-reviewedMicrobiology