Pharmacology & ToxicologybioRxiv
Novel enhancers of guanylyl cyclase-A activity via allosteric modulation
H. Andresen, C. Perez-Ternero, J. Robinson…·L. R. Moltzau
The paper identifies small molecule allosteric enhancers of GC-A that increase ANP and BNP signaling without using known binding sites or mechanisms.
DOI 10.1111/bph.16203