NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma
E. Katab, A. J. Kumar, K. Steiger, J. Mergner, M. Azkargorta, A. Yeroslaviz, F. Elortza, V. Fernandez-Saiz
The paper identifies the c-REL-OTUD4 axis as a regulator of BCR in B-cell lymphoma, showing OTUD4 stabilizes c-REL and BCR, and its downregulation inhibits lymphoma cell growth.
bioRxiv · May 6, 2023 · PreprintCancer Biology